Open Access and Peer-reviewed
Home Journal Issues Guide for Authors Editorial Board Aims & Scope About Journal News & Announcements


Original Research (Original Article) 
JVS. 2019; 5(1): 46-54
doi: 15837


Evaluation of Turkey Humoral Immune Response to Avian Influenza and Turkey Rhinotracheitis Viruses Vaccines

Rana A. Rabiea; Fawzy M.; Khodeir M. H. and EL Tarabili M. M..

Abstract
Background: Turkeys are susceptible to many virus diseases such as turkey rhinotracheitis (TRT) and avian influenza (AI) that affect their populations in a dramatic form. The successful control of those viral diseases depends on well-designed vaccination programs using high potent safe vaccines.
Aim: The present study investigated the effect of inactivated AI vaccine and live attenuated TRT vaccine on the immune response of turkey chickens when administrated in a mutual manner.
Methods: Four groups of bronzy turkey chickens were used in this study; group-1 received TRT vaccine, group-2 received AI vaccine, group-3 received TRT and AI vaccines and group-4 served as control. The humoral immune response evaluated serologically by using haemagglutination inhibition test (HIT), serum neutralization test (SNT) and Indirect Enzyme-Linked Immune Sorbent Assay (ELISA).
Results: Monitoring of TRT virus antibody titers by SNT, it was found detectable TRT antibody titers by the first week post vaccination as 4 in group-1 and 2 in group-3. Both groups showed peak SNT titer (256) of TRT virus by the third-week post administration of the second dose and remain stable up to 24 weeks post vaccination. Following up avian influenza antibody titers using HI test, it was found detectable antibodies against AIV reached their peak titer (64) by the second week after receiving the second dose in group-2 and group-3 then began to decrease in both groups by third-week post the second dose to reach the zero level at week twenty-four. The results of SNT and HIT confirmed using ELISA.
Conclusion: There is no antagonizing effect between the two vaccines on the immune response of turkey chickens against each other where all vaccinated birds exhibited good levels of specific TRT and AI antibodies. Therefore, it is possible to vaccinate turkeys simultaneously against TRT and AI safely and potently.

Key words: Turkey, Avian Influenza, turkey rhinotracheitis, vaccine.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Rana A. Rabiea; Fawzy M.; Khodeir M. H. and EL_Tarabili M. M.
on Google
on Google Scholar
Article Statistics
 Viewed: 2060
Downloaded: 94


How to Cite this Article
Pubmed Style

Rabiea RA, M. F, . Evaluation of Turkey Humoral Immune Response to Avian Influenza and Turkey Rhinotracheitis Viruses Vaccines. JVS. 2019; 5(1): 46-54. doi:15837


Web Style

Rabiea RA, M. F, . Evaluation of Turkey Humoral Immune Response to Avian Influenza and Turkey Rhinotracheitis Viruses Vaccines. http://www.j-virol-sci.com/?mno=15837 [Access: March 28, 2020]. doi:15837


AMA (American Medical Association) Style

Rabiea RA, M. F, . Evaluation of Turkey Humoral Immune Response to Avian Influenza and Turkey Rhinotracheitis Viruses Vaccines. JVS. 2019; 5(1): 46-54. doi:15837



Vancouver/ICMJE Style

Rabiea RA, M. F, . Evaluation of Turkey Humoral Immune Response to Avian Influenza and Turkey Rhinotracheitis Viruses Vaccines. JVS. (2019), [cited March 28, 2020]; 5(1): 46-54. doi:15837



Harvard Style

Rabiea, R. A., M., . F. & (2019) Evaluation of Turkey Humoral Immune Response to Avian Influenza and Turkey Rhinotracheitis Viruses Vaccines. JVS, 5 (1), 46-54. doi:15837



Turabian Style

Rabiea, Rana A., Fawzy M., and Khodeir M. H. and EL_Tarabili M. M.. 2019. Evaluation of Turkey Humoral Immune Response to Avian Influenza and Turkey Rhinotracheitis Viruses Vaccines. Journal of Virological Sciences, 5 (1), 46-54. doi:15837



Chicago Style

Rabiea, Rana A., Fawzy M., and Khodeir M. H. and EL_Tarabili M. M.. "Evaluation of Turkey Humoral Immune Response to Avian Influenza and Turkey Rhinotracheitis Viruses Vaccines." Journal of Virological Sciences 5 (2019), 46-54. doi:15837



MLA (The Modern Language Association) Style

Rabiea, Rana A., Fawzy M., and Khodeir M. H. and EL_Tarabili M. M.. "Evaluation of Turkey Humoral Immune Response to Avian Influenza and Turkey Rhinotracheitis Viruses Vaccines." Journal of Virological Sciences 5.1 (2019), 46-54. Print. doi:15837



APA (American Psychological Association) Style

Rabiea, R. A., M., . F. & (2019) Evaluation of Turkey Humoral Immune Response to Avian Influenza and Turkey Rhinotracheitis Viruses Vaccines. Journal of Virological Sciences, 5 (1), 46-54. doi:15837








AUTHOR LOGIN

REVIEWER LOGIN

Indexed
&
Abstracted



ABOUT JOURNAL
POLICIES
STATEMENTS

This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access.

The articles in Journal of Virological Sciences are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.